Redox Biology of Peroxisome Proliferator-Activated Receptor-γ in Pulmonary Hypertension
نویسندگان
چکیده
منابع مشابه
Peroxisome proliferator-activated receptor-γ ameliorates pulmonary arterial hypertension by inhibiting 5-hydroxytryptamine 2B receptor.
An elevated plasma level of 5-hydroxytryptamine (5-HT) or upregulation of 5-HT receptor signaling or both is implicated in vascular contraction and remodeling in pulmonary arterial hypertension (PAH). Recently, peroxisome proliferator-activated receptor-γ (PPARγ) agonists have been shown to ameliorate PAH. However, their effects on the 5-HT-induced contraction of pulmonary arteries remain unkno...
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ژورنال
عنوان ژورنال: Antioxidants & Redox Signaling
سال: 2019
ISSN: 1523-0864,1557-7716
DOI: 10.1089/ars.2018.7695